Audiology - Communication Research
https://audiolcommres.org.br/article/doi/10.1590/2317-6431-2024-2963pt
Audiology - Communication Research
Original Article

Risco de alterações no neurodesenvolvimento de crianças de 18 meses nascidas de mães infectadas pela SARS-CoV-2

Risk of neurodevelopmental changes in 18-month-old children born to mothers infected with SARS-CoV-2

Livia Maria Silva; Maria Luisa de Oliveira Melo; Matheus Francoy Alpes; Carla Manfredi dos Santos

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Resumo

Objetivo: Investigar risco de alterações no desenvolvimento infantil de crianças de 18 meses nascidas de mães que foram infectadas pelo vírus SARS-CoV-2 durante a gestação e identificar possíveis atrasos em indicadores de desenvolvimento.

Métodos: Participaram da pesquisa 41 crianças que nasceram no período de janeiro de 2021 a agosto de 2021, cujas mães testaram positivo para a Covid-19 durante a gestação. Para a investigação do desenvolvimento linguístico, motor, cognitivo e social foi utilizado o Ages & Stages Questionnaires nos cinco domínios: Comunicação, Coordenação Motora Ampla, Coordenação Motora Fina, Resolução de Problemas e Pessoal/Social. Os dados foram descritos por meio de frequências absolutas e percentuais e por meio de média, desvio padrão, mínimo, mediana e máximo. Para analisar a associação entre as variáveis de interesse foi utilizado o modelo de regressão de Poisson. O pós-teste de Tukey foi utilizado para as comparações múltiplas.

Resultados: Os domínios Pessoal/-Social, Coordenação Motora Fina e Resolução de Problemas, neste seguimento, foram os de melhor desempenho. O pior desempenho foi observado no domínio Comunicação, seguido da Coordenação Motora Ampla. A prematuridade, peso ao nascimento, índice de Apgar e necessidade de internação da criança pós-nascimento foram variáveis associadas ao baixo desempenho nos domínios avaliados.

Conclusão: Foi observado risco de atraso no desenvolvimento de crianças de 18 meses nascidas de mães que foram contaminadas pelo vírus SARS-CoV-2 durante a gestação. O domínio com maior prejuízo foi o de Comunicação, seguido de alteração da Coordenação Motora Ampla.

Palavras-chave

Triagem; Diagnóstico precoce; Síndrome pós-Covid-19 aguda; Desenvolvimento da linguagem; Fonoaudiologia

Abstract

Purpose: To investigate the risk of child development in 18-month-old children born to mothers who were infected by the SARS-CoV-2 virus during pregnancy and identify possible delays in development indicators.

Methods: Children who were born between January 2021 and August 2021, whose mothers tested positive for COVID-19 during pregnancy, participated in the research. To investigate linguistic, motor, cognitive and social development, the Ages & Stages Questionnaires (ASQ-3) was used in the five domains: Communication, Gross motor coordination, Fine motor coordination, Problem solving and Personal/social. Data were described using absolute and percentage frequencies and using mean, standard deviation, minimum, median and maximum. To analyze the association between the variables of interest, the Poisson regression model was used. Tukey's post-test was used for multiple comparisons.

Results: The Personal-Social domains, followed by Fine motor coordination and Problem Solving were the best performing. The worst performance was observed in the Communication domain, followed by Gross motor coordination. Prematurity, birth weight, Apgar score and need for hospitalization of the child after birth were variables associated with low performance in the domains assessed.

Conclusion: A risk of developmental delay was observed in 18-month-old children born to mothers who were infected with the SARS-CoV-2 virus during pregnancy. The domain with the greatest loss was Communication, followed by changes in Gross Motor Coordination.

Keywords

Triage; Early diagnosis; Post-acute Covid-19 syndrome; Language development; Speech, language and hearing sciences

References

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Submitted date:
07/13/2024

Accepted date:
12/10/2024

698f7c28a9539576085b5363 acr Articles
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